
Cordyceps sinensis extract Cordyceps Polysaccharide Cordycepin Extract Adenosine Extract supplier
Active ingredients: Polysaccharides, Cordycepin, Adenosine
Detection method: HPLC/Phenol-Sulfuric Acid Method
Extraction solvent: water
Appearance: Light brown to brown powder/Light yellow to yellow powder/White to off-white powder
Wholesale packaging: 25 kg/barrel
Expiration period: 2 years
- Herbfields Cordyceps Sinensis Extract Specification:
Cordyceps sinensis, also known as Cordyceps sinensis, is a traditional Chinese medicinal material with a long history. As early as "Shen Nong's Materia Medica", there are records about Cordyceps sinensis, which is widely known as a nourishing and strong medicinal material. At first, people mainly obtained Cordyceps sinensis through wild picking. Due to its unique growth environment, it mainly grows in high-altitude areas of the Qinghai-Tibet Plateau and is scarce in quantity.
- Effects of Cordyceps Sinensis Extract
Cordyceps sinensis is known as the "gold of medicine" and has a variety of pharmacological effects and healthcare effects. According to relevant research, Cordyceps Sinensis has the following main effects:
Enhance immunity: Cordyceps sinensis can enhance the body's immune function and improve the body's resistance by promoting the activity of macrophages and natural killer cells (NK cells).
Anti-tumor effect: Multiple studies have shown that the cordycepin in Cordyceps Sinensis has a significant anti-tumor effect and can inhibit the growth and spread of cancer cells.
Antioxidant and anti-aging: The polysaccharides in Cordyceps sinensis extract have good antioxidant effects, which can fight against free radicals and slow down the aging process.
Anti-inflammatory effect: The active ingredients in Cordyceps sinensis, such as cordycepin and polysaccharides, can significantly inhibit the production of inflammatory factors and thus exert anti-inflammatory effects.
- Cordyceps Sinensis Extract Raw materials and active ingredients
- Cordyceps Sinensis
The main source of Cordyceps sinensis is the Qinghai-Tibet Plateau, which has a unique growth environment and extremely demanding environmental requirements. As demand increases and wild resources decrease, artificial cultivation becomes a reliable approach. Artificially cultivated Cordyceps sinensis is mainly concentrated in Yunnan, Sichuan, Qinghai and other places in my country. The advancement of cultivation technology has continuously improved the output and quality of artificial Cordyceps Sinensis.
- Active ingredients in Cordyceps Sinensis
The active ingredients in Cordyceps sinensis are diverse, including cordycepin, adenosine, polysaccharides, amino acids, and a variety of vitamins and minerals.
- Cordycepin: It is a nucleoside analogue with a wide range of biological activities, especially in anti-tumor and anti-viral effects.
- Adenosine: Helps dilate blood vessels, improves blood circulation, and also has certain analgesic and anti-inflammatory effects.
- Polysaccharides: have various pharmacological effects such as immunomodulation, antioxidant, and anti-tumor.
- Cordyceps Sinensis Extract Extraction technology
The production process of Cordyceps sinensis extract is particularly critical, which directly affects the quality stability and biological activity of the product. The advancement of modern science and technology has led to continuous innovation in the production technology of Cordyceps sinensis extract. The main extraction techniques include the following:
1. Supercritical fluid extraction method
Supercritical fluid extraction technology is widely used in the field of plant extraction. It uses supercritical fluid (such as carbon dioxide) as a solvent to extract active ingredients under high-pressure conditions. This method is efficient, environmentally friendly, and can maintain the activity of heat-sensitive and easily oxidized components in Cordyceps Sinensis.
2. Water extraction and alcohol precipitation method
Water extraction and alcohol precipitation is a commonly used extraction process for traditional Chinese medicine. The water-soluble components in Cordyceps sinensis are extracted with hot water, and then the polysaccharides are separated and purified by alcohol precipitation. This method is simple to operate and suitable for large-scale industrial production.
3. Biological enzymatic extraction method
This method uses biological enzymes to enzymatically hydrolyze Cordyceps sinensis, which can efficiently decompose the cell wall and release the active ingredients within the cell. The enzymatic extraction method has the advantages of mildness and few side effects and has gradually become a hot topic in the industry.
Detailed explanation of the process of extracting Cordyceps Sinensis
The extraction process of Cordyceps sinensis is the core step to obtain its active ingredients. Scientific and reasonable extraction methods can not only improve the extraction efficiency but also ensure the activity and stability of the active ingredients.
- Detailed process flow for producing Cordyceps sinensis extract:
1. Raw material preparation
Material selection: Select high-quality Cordyceps sinensis and avoid using contaminated or deteriorated raw materials to ensure the high purity and high activity of the extract.
Cleaning: Thoroughly clean the sediment and impurities on the surface of Cordyceps sinensis to prevent these impurities from affecting product quality during the extraction process1.
Drying: The cleaned Cordyceps sinensis is dried, often using a low-temperature drying method to maintain the stability of its internal components. The drying temperature is generally controlled at 60-80°C, and the drying time is about 12 hours.
2. Crush
The dried Cordyceps sinensis is pulverized into fine powder, which increases its specific surface area and is conducive to full extraction. Commonly used crushing equipment includes ball mills, hammer mills, etc.
3. Soaking
Soak the crushed Cordyceps sinensis powder in an appropriate amount of water to fully dissolve the active ingredients. The soaking time is generally 1-2 hours. The purpose of soaking is to diffuse the active ingredients inside the cordyceps and promote the subsequent extraction process.
4. Decoction
Heat the soaked Cordyceps sinensis powder together with the soaking liquid to a boil, then reduce the heat to low and simmer for 1-2 hours. During the decoction process, water can be added appropriately to ensure that the active ingredients are fully dissolved1.
5. Filtering
The decoction mixture is filtered to separate the liquid and solid residue. The obtained liquid contains a large amount of active ingredients, and the solid residue can be extracted again to ensure full utilization of resources1.
6. Concentration
The filtered medicinal solution is concentrated to reduce the liquid volume and increase the concentration of active ingredients. The temperature must be strictly controlled during the concentration process, generally not exceeding 60°C, to avoid high temperatures destroying the activity of the active ingredients.
7. Alcohol sedimentation
In order to further purify the active ingredients, a certain proportion of ethanol can be added to the concentrated medicinal solution for alcohol precipitation. The amount of ethanol added is generally 1.5-2 times the volume of the liquid. Stir evenly and let it sit for 4-8 hours to fully precipitate macromolecules such as polysaccharides and proteins.
8. Filter again
The alcohol-precipitated mixture was filtered again, and the precipitate and supernatant were separated. The precipitate is the main active ingredient of Cordyceps sinensis. After further drying, it can be made into powder or other forms of products, and the supernatant can be recycled and processed8.
9. Drying
The active ingredient precipitation obtained by alcohol precipitation is dried, and the drying temperature is controlled at 60-80°C. The drying time depends on the specific situation, usually about 12 hours. The drying process is required to maintain stable low-temperature conditions as much as possible to prevent the active ingredients from being reduced in activity due to high temperatures.
10. Crushing and packaging
The dried active ingredients of Cordyceps sinensis can be crushed again into fine powder for easy packaging and subsequent use. The crushed products are then weighed, mixed, and finally sealed and packaged to avoid moisture and oxidation to ensure product quality and stability.
Temperature control: During the entire extraction process, especially the soaking, decoction, and drying steps, temperature control is particularly critical. Excessive temperature will destroy the heat-sensitive components in Cordyceps Sinensis.
Equipment cleaning: All equipment must be thoroughly cleaned before use to avoid contamination from impurities.
Quality control: Strict quality control is required at every step in the extraction process to ensure the purity of the product
Usually, Cordyceps sinensis is extracted using water as the main solvent.
- Advantages of water as a solvent:
- Water is a safe, environmentally friendly, non-toxic natural solvent and conforms to the concept of green chemistry.
- Water can effectively dissolve polar components such as polysaccharides and proteins in Cordyceps sinensis, and the extraction efficiency is high.
- Water extract has higher safety and bioavailability, and is more suitable for preparing health products and medicines.
- Specific steps for water extraction:
- Mix dry Cordyceps sinensis powder with the appropriate amount of water and soak for extraction.
- Heat the soaking liquid and cook it to promote the dissolution of the active ingredients.
- The extract is separated by filtration and subjected to subsequent purification such as concentration and alcohol precipitation.
- Finally, water-soluble Cordyceps sinensis extract was obtained.
- Optimization of water extraction:
- Optimize extraction efficiency by adjusting soaking time, temperature, solid-liquid ratio, and other parameters.
- Ultrasonic waves, microwaves, and other auxiliary means are used to further improve the extraction rate and yield.
- Combined with other separation technologies such as membrane separation, chromatography, etc., the purity of the extract can be improved.
Water extraction is the mainstream method for extracting Cordyceps Sinensis, which can fully retain its natural biologically active ingredients and is suitable for the production of health care products and pharmaceuticals. With the continuous advancement of technology, the water extraction process is also constantly optimized, and the extraction efficiency and product quality are constantly improving.
Market product specifications and applications
Currently, there are various types of cordyceps extract products on the market with different specifications, mainly classified according to purity and application fields. Common specifications include:
- Cordycepin purity: different purity levels such as less than 5%, 5%-10%, 10%-20%, and above 20%.
- Polysaccharide content: 20%-30%, 30%-50%, more than 50%, etc.
- Adenosine content: 0.1%-0.5%, 0.5%-1%, more than 1%, etc.
Cordyceps sinensis extract is widely used in health products, medicines, cosmetics, and other fields, and the product forms also have their own characteristics:
- Health products: Cordyceps sinensis extract is used as the main ingredient and is made into capsules, tablets, oral liquids, and other forms. It has the effect of replenishing the liver and kidneys and enhancing immunity.
- Drugs: Cordyceps sinensis extract is made into injections or powders, which are used to treat chronic bronchitis, tuberculosis, and other diseases, and are widely used clinically.
- Cosmetics: Due to its antioxidant and anti-aging effects, Cordyceps sinensis extract is often used to make skin care products, beauty masks, etc., to delay skin aging and improve skin quality.
- Cordyceps Sinensis Extract Market Analysis
1. Demand trends
As people's health awareness and living standards improve, the market demand for cordyceps extract continues to grow. Especially in the Asia-Pacific region, where the traditional Chinese medicine health care culture is profound, the market prospects for cordyceps extract products are broad. In recent years, in Europe and North America, the demand for health products aimed at improving immunity and anti-fatigue has increased, and Cordyceps sinensis extract has gradually attracted the attention of consumers in these regions.
2. Price trends
Due to the scarcity and high collection cost of wild Cordyceps sinensis, market prices are generally high. The technological progress and large-scale production of artificially cultivated Cordyceps sinensis have made its price relatively stable and controllable. With the continuous advancement of extraction technology, the production cost of extract products is expected to be further reduced, thus driving the market price to become more rational.
3. Market competition
The cordyceps extract market is highly competitive, mainly focusing on product quality and brand. Companies with advanced extraction technology and strict quality control systems occupy market advantages. At the same time, as consumers pay more attention to product safety and effectiveness, products with good quality certification and third-party testing reports are more popular.
4. Market drivers
Increased health awareness: People’s emphasis on health is increasing year by year, driving the growth in demand for functional health products.
Scientific research progress: Continuous and in-depth scientific research has revealed more pharmacological effects of Cordyceps Sinensis and improved its market recognition.
Policy support: The international promotion of traditional Chinese medicine and policy support provides a good environment for the market expansion of cordyceps extract.
5. Challenges and opportunities
Protection of wild resources: Over-harvesting of Cordyceps sinensis poses a threat to wild resources, and resource protection has become an important issue for industry development.
Technological breakthrough: Technological innovation and standardized production of extraction processes are important means to improve product quality and reduce production costs.
Market supervision: As the market expands, the improvement and strict implementation of regulatory policies are crucial to maintaining market order and consumer trust.
The market demand for Cordyceps sinensis extract is growing steadily due to its excellent pharmacological effects and wide application prospects. The advancement of modern science and technology has provided strong support for the extraction and application of Cordyceps sinensis.
